Rey Mysterio, born Óscar Gutiérrez Rubio, is a celebrated American professional wrestler known for his pioneering role in popularizing lucha libre and cruiserweight wrestling in the U.S. He is a WWE Hall of Famer and has numerous championship titles to his name.
This is based on winning 8 head-to-head matchups with other famous people, but also losing 19 head-to-head matchups.
Most recently Rey Mysterio lost a matchup to Maria Callas (#1850) voted by someone from Canada.