Pope John Paul II, born Karol Wojtyła, was the head of the Catholic Church from 1978 to 2005. Known for his efforts to improve interfaith relations and for his extensive travels, he beatified and canonized more people than any previous pope.
This is based on winning 59 head-to-head matchups with other famous people, but also losing 67 head-to-head matchups.
Most recently Pope John Paul II lost a matchup to Elton John (#149) voted by someone from United States.