Nancy Reagan was an American actress and First Lady of the United States from 1981 to 1989. Known for the 'Just Say No' campaign against drug use, she also had significant influence during her husband's presidency.
This is based on winning 3 head-to-head matchups with other famous people, but also losing 13 head-to-head matchups.
Most recently Nancy Reagan lost a matchup to Anne Hathaway (#57) voted by someone from United States.